Anabolic-Matrix Rx™ contains the highest quality herbal extracts and ingredients available. The Tribulus Terrestris in our formula contains a minimum of 20% Protodioscin, the active ingredient that raises LH (Leutenizing Hormone) levels. Most Tribulus based supplements on the market do not contain a high quality Tribulus extract and will do absolutely nothing! Our formula is all natural and completely unique combining high amounts of Tribulus Terrestris (40% extract), Tongkat Ali (20:1 extract), Diindolemethane, Maca Root, 5,7-Dihydroxyflavone, Dehydroepiandrosterone (DHEA) and Bioperine®, and has been shown to naturally increase Testosterone levels up to 150%!
Below is an illustration Hypothalamic-Pituitary-Gonadal Axis (also HPG Axis), ANABOLIC-MATRIX Rx is designed to maximize natural testosterone levels without interrupting the natural HPG Axis.
Clinical Research Studies:
Aphrodisiac properties of Tribulus Terrestris extract (Protodioscin) in normal and castrated rats.
Author: Gauthaman K , Adaikan PG , Prasad RN
Source: Life Sci, 71(12): 1385-96 2002
Tribulus terrestris (TT) has long been used in the traditional Chinese and Indian systems of medicine for the treatment of various ailments and is popularly claimed to improve sexual functions in man. Sexual behaviour and intracavernous pressure (ICP) were studied in both normal and castrated rats to further understand the role of TT containing protodioscin (PTN) as an aphrodisiac. Adult Sprague-Dawley rats were divided into five groups of 8 each that included distilled water treated (normal and castrated), testosterone treated (normal and castrated, 10 mg/kg body weight, subcutaneously, bi-weekly) and TT treated (castrated, 5 mg/kg body weight, orally once daily). Decreases in body weight, prostate weight and ICP were observed among the castrated groups of rats compared to the intact group. There was an overall reduction in the sexual behaviour parameters in the castrated groups of rats as reflected by decrease in mount and intromission frequencies (MF and IF) and increase in mount, intromission, ejaculation latencies (ML, IL, EL) as well as post-ejaculatory interval (PEI). Compared to the castrated control, treatment of castrated rats (with either testosterone or TT extract) showed increase in prostate weight and ICP that were statistically significant. There was also a mild to moderate improvement of the sexual behaviour parameters as evidenced by increase in MF and IF; decrease in ML, IL and PEI. These results were statistically significant. It is concluded that TT extract appears to possess aphrodisiac activity probably due to androgen increasing property of TT (observed in our earlier study on primates).
Eurycoma Longifolia Jack (Tongkat Ali) enhances libido in sexually experienced male rats.
Author: Ang HH, Sim MK.
Source: School of Pharmaceutical Sciences, University of Science Malaysia, Penang, Malaysia.
The effects of Eurycoma longifolia Jack were studied on the libido of sexually experienced male rats after dosing them with 200, 400 and 800 mg/kg body weight twice daily of different fractions of E. longifolia Jack for 10 days. Results showed that E. longifolia Jack produced a dose-dependent increase in mounting frequency of the treated animals with 400 mg/kg of chloroform, methanol, water and butanol fractions resulting in mounting frequencies of 5.3 +/- 1.2, 4.9 +/- 0.7, 4.8 +/- 0.7 and 5.2 +/- 0.1, and 800 mg/kg further increased them to 5.4 +/- 0.8, 5.4 +/- 0.8, 5.2 +/- 0.6 and 5.3 +/- 0.2 respectively but there were no erections, intromissions, ejaculations or seminal emissions during the 20-min observation period which allowed for the measurement of sexual arousal reflected by mounting frequency uninfluenced by other behavioural components. This study provides evidence that E. longifolia Jack is a potent stimulator of sexual arousal in sexually vigorous male rats in the absence of feedback from genital sensation.
PMID: 9353636 [PubMed - indexed for MEDLINE]
Clinical Research Study on Diindolylmethane (DIM):
TITLE: Multifunctional aspects of the action of indole-3-carbinol as an antitumor agent.
Authors: Bradlow HL; Sepkovic DW; Telang NT; Osborne MP
Author Affiliation: Strang Cancer Research Laboratory,
New York, New York 10021, USA.
Previous studies from this laboratory have suggested that 2-hydroxyestrone is protective against breast cancer, whereas the other principal metabolite, 16 alpha-hydroxyestrone, and the lesser metabolite quantitatively, 4-hydroxyestrone, are potent carcinogens. Attempts to directly decrease the formation of the 16-hydroxylated metabolite were either unsuccessful or required such high levels of the therapeutic agent as to be impractical. On the other hand the concentration of the protective metabolite, 2-hydroxyestrone, proved to be readily modulated by a variety of agents, both in the direction of increased protection and the opposite direction, increased risk by a variety of agents and activities. We have focussed our attention on indole-3-carbinol, a compound found in cruciferous vegetables, and its further metabolites in the body, diindolylmethane (DIM) and indolylcarbazole (ICZ), because of its relative safety and multifaceted activities. It has been shown that it induces CyP4501A1, increasing 2-hydroxylation of estrogens, leading to the protective 2-OHE1, and also decreases CyP1B1 sharply, inhibiting 4-hydroxylation of estradiol, thereby decreasing the formation of the carcinogenic 4-OHE1. In addition to these indirect effects as a result of altered estrogen metabolism, indole-3-carbinol has been shown to have direct effects on apoptosis and cyclin D, resulting in blockage of the cell cycle. In addition to its antitumor activity in animals, it has also been shown to be effective against HPV-mediated tumors in human patients. All of these responses make the study of its behavior as a therapeutic agent of considerable interest. Structure-Activity Relationship
Scientific Reports on Maca Root
Scientist Gustavo Gonzalez of Peru's Cayetano Heredia University, who led what the scientists say is the world's first study into maca's effect on humans, told a news conference the three-month trial involving 12 volunteer men pointed to an 180-200 percent lift in libido and up to a doubling of sperm production.
"It's a miracle (product)," said Dr. Fernando Cabieses, a professor and authority on maca. The plant, he said, was a nutritional gem for people of all ages.
The studies were preliminary and not subject to independant review and confirmation, factors which may influence the degree to which the research is accepted by other scientists. But experts said the data so far was promising.
"According to reports from the international medical community, the plant definitely has energy giving properties, boosts physical and sexual performance... Preliminary reports are promising," Julio Castro, dean of Peru's College of Doctors told Reuters.